Welcome to the McMahon Lab
Microbes are amazing. Scientists and engineers are only beginning to understand and exploit the metabolic potential of these organisms and their communities. The broad objective of my research program is to improve our capacity to predict and model microbial behavior, while searching for novel biologically mediated transformations that can be harnessed for engineering applications.
My students and I study the microbial ecology of both natural and engineered systems. We use molecular tools to investigate microbial community structure and function in lakes and activated sludge. Our partnership with the North Temperate Lakes Long Term Ecological Research program provides rich contextual data for our studies of lake bacterial community ecology. We are particularly interested in phosphorus, nitrogen, and carbon cycling in lakes and how this relates to eutrophication and water quality. We are using highly resolved time series sampling of multiple lakes, combined with metagenomics and meta-transcriptomics to explore how different lineages of freshwater bacteria contribute to this cycling.
We are also engaged in metagenomic and post-genomic approaches to dissecting the metabolism of bacteria specialized in the sequestration of phosphorus in activated sludge. This information will ultimately lead to the construction of more predictive mechanistic and ecosystem-scale models to describe such processes as wastewater treatment and freshwater nutrient cycling.
- Synthesizing Laboratory and Field Experiments to Quantify Dominant Transformation Mechanisms of 2,4-Dichlorophenoxyacetic Acid (2,4-D) in Aquatic Environments. (2022). Environmental Science & Technology
- Reevaluation of the Phylogenetic Diversity and Global Distribution of the Genus ” Candidatus Accumulibacter”. (2022). mSystems
- Pilot-scale comparison of biological nutrient removal (BNR) using intermittent and continuous ammonia-based low dissolved oxygen aeration control systems. (2022). Water Science and Technology
- McDaniel EA, Moya-Flores F, Keene Beach N, Camejo PY, Oyserman BO, Kizaric M, Khor EH, Noguera DR, McMahon KD (2021) Metabolic Differentiation of Co-occurring Accumulibacter Clades Revealed through Genome-Resolved Metatranscriptomics. mSystems 6((4)):e0047421